Intestinal Polyposis Associated with Melanosis Oris

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Intestinal polyposis associated with melanosis oris.

Weber (1919) described a case of acute intussusception in one of a pair of twins originally noticed by Hutchinson (1896) to have oral pigmentation. Peutz (1921) recorded a family of seven, and Jeghers, McKusick and Katz (1949) reported 10 cases of melanosis of the lips and buccal mucosa together with polyposis of the gastro-intestinal tract. The latter's report included a review of the literatu...

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Intestinal polyposis syndromes, such as familial adenomatous polyposis (FAP) and Cowden's syndrome, are often associated with extraintestinal manifestations, and while many of these manifestations are benign, malignant extraintestinal manifestations, such as differentiated thyroid cancers, do occur. Although differentiated thyroid cancers (ie, papillary and follicular thyroid carcinomas) are as...

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Prostate melanosis is an uncommon lesion of uncertain etiology where melanin deposition is seen in the epithelium, in the stroma, or in the form of a blue nevus. There are three reports in the literature of melanosis seen in association with prostatic adenocarcinoma. This is the fourth report of this association.

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Familial polyposis is of interest for its own sake as a sort of pathological curiosity and also in relation to the problem of cancer. The term " polyposis " is used to describe a widespread adenomatous proliferation of the intestinal mucous membrane, leading to the formation of multiple adenomata. It should not be applied to intestinal polyps of different histological structure, such as inflamm...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1954

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.29.147.455